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Mark Pegram Selected Research

Paclitaxel (Taxol)

3/2016Phase 1b/2a study of trastuzumab emtansine (T-DM1), paclitaxel, and pertuzumab in HER2-positive metastatic breast cancer.
7/2002Long term follow-up of patients with recurrent ovarian cancer after Ad p53 gene replacement with SCH 58500.

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Mark Pegram Research Topics

Disease

42Breast Neoplasms (Breast Cancer)
11/2023 - 01/2002
24Neoplasms (Cancer)
05/2023 - 01/2002
7Disease Progression
11/2023 - 11/2009
5Neoplasm Metastasis (Metastasis)
11/2023 - 08/2006
5Brain Neoplasms (Brain Tumor)
11/2023 - 08/2006
4Triple Negative Breast Neoplasms
10/2021 - 02/2011
3Diarrhea
01/2020 - 11/2009
3Carcinoma (Carcinomatosis)
11/2002 - 01/2002
2Vomiting
01/2020 - 11/2012
2Nausea
01/2020 - 11/2012
2Thrombocytopenia (Thrombopenia)
01/2017 - 11/2012
2Leukemia
11/2010 - 01/2010
2Cardiotoxicity
01/2010 - 01/2003
2Exanthema (Rash)
11/2009 - 06/2005
1Pathologic Complete Response
10/2021
1Circulating Neoplastic Cells
01/2020
1Fatigue
01/2020
1Cardiovascular Diseases (Cardiovascular Disease)
10/2019
1Metabolic Brain Diseases (Encephalopathy, Metabolic)
01/2017
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2017
1Sepsis (Septicemia)
01/2017
1Peripheral Nervous System Diseases (PNS Diseases)
03/2016
1Hypoxia (Hypoxemia)
03/2010

Drug/Important Bio-Agent (IBA)

18Trastuzumab (Herceptin)FDA Link
11/2023 - 01/2003
11Hormones (Hormone)IBA
06/2023 - 01/2003
10human ERBB2 proteinIBA
05/2023 - 11/2009
6ErbB Receptors (EGF Receptor)IBA
06/2023 - 06/2005
6Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2002
6taxaneIBA
10/2021 - 01/2003
6Lapatinib (GW572016)FDA Link
01/2020 - 11/2009
5pertuzumabIBA
11/2023 - 03/2016
5Capecitabine (Xeloda)FDA Link
01/2023 - 11/2010
5Estrogen ReceptorsIBA
01/2023 - 02/2011
4Progesterone Receptors (Progesterone Receptor)IBA
01/2023 - 02/2011
4AnthracyclinesIBA
10/2021 - 01/2003
4AntibodiesIBA
01/2021 - 08/2006
4Epidermal Growth Factor (EGF)IBA
01/2021 - 07/2006
4Ado-Trastuzumab EmtansineIBA
01/2020 - 11/2012
4PlatinumIBA
09/2004 - 07/2002
3Phosphotransferases (Kinase)IBA
06/2023 - 09/2007
3Estrogens (Estrogen)FDA Link
05/2023 - 11/2011
3Taxoids (Taxanes)IBA
10/2021 - 11/2010
3Immunoconjugates (Immunoconjugate)IBA
01/2021 - 01/2017
3DNA (Deoxyribonucleic Acid)IBA
01/2021 - 04/2002
3Letrozole (Femara)FDA LinkGeneric
11/2011 - 11/2009
2tucatinibIBA
01/2023 - 01/2020
2neratinibIBA
01/2020 - 10/2017
2Transaminases (Aminotransferases)IBA
01/2020 - 11/2012
2Tyrosine Kinase InhibitorsIBA
01/2020 - 11/2009
2NiclosamideFDA Link
07/2016 - 02/2016
2Paclitaxel (Taxol)FDA LinkGeneric
03/2016 - 07/2002
2Monoclonal AntibodiesIBA
03/2008 - 07/2006
2EnzymesIBA
01/2003 - 04/2002
2raltitrexed (D 1694)IBA
04/2002 - 01/2002
2NB1011IBA
04/2002 - 01/2002
2Thymidylate SynthaseIBA
04/2002 - 01/2002
1Cyclin DIBA
06/2023
1olaparibIBA
01/2021
1Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2021
1Radioisotopes (Radionuclides)IBA
01/2021
1Messenger RNA (mRNA)IBA
01/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2020
1Biosimilar PharmaceuticalsIBA
10/2019
1Estrogen Receptor Modulators (Antiestrogen)IBA
08/2018
1abemaciclibIBA
08/2018
1Cyclin-Dependent Kinases (cdk Proteins)IBA
08/2018
1ribociclibIBA
08/2018
1palbociclibIBA
08/2018
1Biomarkers (Surrogate Marker)IBA
05/2018
1Diphosphonates (Bisphosphonates)IBA
05/2018
1Circulating Tumor DNAIBA
10/2017
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2017
1Cisplatin (Platino)FDA LinkGeneric
07/2016
1OSM-LIF ReceptorsIBA
08/2012
1AntigensIBA
11/2011
1Immunoglobulins (Immunoglobulin)IBA
11/2011
1epitumomabIBA
11/2011
1Adenosine Triphosphate (ATP)IBA
11/2010
1Mechlorethamine (Nitrogen Mustard)FDA Link
03/2010
1Cytotoxins (Cytolysins)IBA
03/2010
1ProdrugsIBA
03/2010
1Aldo-Keto ReductasesIBA
03/2010
1PR-104AIBA
03/2010
1PR-104IBA
03/2010
1Aromatase InhibitorsIBA
11/2009
1tyrosine receptor (receptor, tyrosine)IBA
09/2007
1Neoplasm Antigens (Tumor Antigens)IBA
09/2007
1Complementary DNA (cDNA)IBA
08/2006
1Capsules (Microcapsules)IBA
08/2006
1CarcinogensIBA
08/2006
1Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA
07/2006
1Growth Factor ReceptorsIBA
07/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2006

Therapy/Procedure

27Therapeutics
05/2023 - 11/2002
11Drug Therapy (Chemotherapy)
10/2021 - 07/2002
4Radiotherapy
11/2023 - 07/2002
3Adjuvant Chemotherapy
10/2021 - 04/2012
1Precision Medicine
01/2020
1Immunotherapy
01/2020
1Biological Therapy
04/2014